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8.—(1) The genetically modified micro-organism should be non-pathogenic.
This requirement is reasonably assured by compliance with all the requirements above.
(2) (a) The genetically modified micro-organism should be as safe (to man and the environment) as the recipient or parental strains (applicable only for Type A operations);
(b)the genetically modified micro-organisms should be as safe in the reactor or fermentor as the recipient or parental strains, but with limited survivability and/or replicability outside the reactor or fermenter without adverse consequences in the environment (applicable only for Type B operations).
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