2024 No. 1101
AGRICULTURE, ENGLAND

The Feed Additives (Authorisations) and Uses of Feed Intended for Particular Nutritional Purposes (Amendment of Commission Regulation (EU) 2020/354) (England) Regulations 2024

Made
Laid before Parliament
Coming into force
The Secretary of State makes these Regulations in exercise of the powers conferred by Articles 9(1), 10(5) and 18A(3) of Regulation (EC) No 1831/2003 of the European Parliament and of the Council on additives for use in animal nutrition1 and sections 74A(1)(a) and (b) of the Agriculture Act 19702.
There has been open and transparent public consultation during the preparation and evaluation of Article 9 of Regulation (EC) No 178/2002 of the European Parliament and of the Council laying down the general principles and requirements of food law, establishing the European Food Safety Authority and laying down procedures in matters of food safety3.

Part 1Introductory

Citation, commencement, extent and application1.

(1)

These Regulations may be cited as the Feed Additives (Authorisations) and Uses of Feed Intended for Particular Nutritional Purposes (Amendment of Commission Regulation (EU) 2020/354) (England) Regulations 2024 and come into force on 20th December 2024.

(2)

These Regulations extend to England and Wales but apply in relation to England only.

Interpretation2.

(1)

In these Regulations —

Regulation (EC) 152/2009” means Commission Regulation (EC) No 152/2009 laying down the methods of sampling and analysis for the official control of feed4.

(2)

Any expression used both in these Regulations and in Regulation (EC) No 1831/2003 of the European Parliament and of the Council on additives for use in animal nutrition or Regulation (EC) No 767/2009 of the European Parliament and of the Council on the placing on the market and use of feed, etc.5 has the same meaning as it has in those Regulations.

(3)

In Schedules 1 to 20, in the tables, in the row relating to “Species or category of animal”, expressions used that are also used in Annex 4 of Commission Regulation (EC) No 429/2008 on detailed rules for the implementation of Regulation (EC) 1831/2003 of the European Parliament and of the Council as regards the preparation and the presentation of applications and the assessment and the authorisation of feed additives (categories and definitions of target animals etc.) have the same meaning as in that Annex.

Part 2Feed additive authorisations

Authorisation of various feed additives3.

(1)

Schedules 1 to 20 (which contain authorisations for feed additives) have effect.

(2)

Subject to Article 14 (renewal of authorisation) of Regulation (EC) No 1831/2003 of the European Parliament and of the Council on additives for use in animal nutrition, the authorisations set out in Schedules 1 to 20 cease to have effect at the end of 19th December 2034.

Part 3Uses of feed intended for particular nutritional purposes

Modification of an essential nutritional characteristic for feed intended to reduce the risk of milk fever and subclinical hypocalcaemia4.

In Commission Regulation (EU) 2020/354 establishing a list of intended uses of feed intended for particular nutritional purposes, etc.6, in the Annex, in Part B (list of intended uses), in entry 60 (reduction of the risk of milk fever and subclinical hypocalcaemia), in column number 2 (essential nutritional characteristics), in the section of the entry starting “Low cations/anions ratio”, for “Objective: 0<DCADs (mEq/kg dry matter) < 100” substitute “Objective: range from -200 mEq/kg dry matter DCADs to < 100 mEq/kg dry matter DCAD”.

Part 4Amendment of assimilated direct legislation

Modification of authorisation: a preparation of Bacillus velezensis (DSM 15544), (identification number 4b1820)5.

(1)

Commission Implementing Regulation (EU) 2016/897 concerning the authorisation of a preparation of Bacillus subtilis (C-3102) (DSM 15544) as a feed additive for laying hens and ornamental fish, etc.7, is amended as follows—

(a)

omit Articles 2 to 4;

(b)

in the Annex, in the table:

(i)

in the second column (name of the holder of authorisation), for “Asahi Calpis Wellness” to the end substitute “Asahi Biocycle Co., Ltd”;

(ii)

in the third column (additive) and the fourth column (composition, etc.), for “Bacillus subtilis C-3102”, in each place, substitute Bacillus velezensis;

(iii)

in the fifth column (species or category of animal), omit “Laying hens”;

(iv)

in the seventh column (minimum content), omit “3 x 108”.

(2)

In Commission Implementing Regulation (EU) 2017/2312 concerning the authorisation of a new use of the preparation of Bacillus subtilis C-3102 (DSM 15544) as a feed additive for sows, suckling piglets and dogs, etc.8, in the Annex, the table is amended as follows—

(a)

in the second column (name of the holder of authorisation), for “Asahi Calpis Wellness” to the end substitute “Asahi Biocycle Co., Ltd”;

(b)

in the third column (additive) for “Bacillus subtilis” substitute Bacillus velezensis;

(c)

in the fourth column (composition, etc.)—

(i)

in the section headed “Additive composition”, for “Bacillus subtilis C-3102” substitute Bacillus velezensis;

(ii)

in the section headed “Characterisation of the active substance”, for “Bacillus subtilis” substitute Bacillus velezensis.

(3)

In Commission Implementing Regulation (EU) 2018/1081 concerning the authorisation of the preparation of Bacillus subtilis C-3102 (DSM 15544) as a feed additive for pigs for fattening, etc.9, in the Annex, the table is amended as follows—

(a)

in the second column (name of the holder of authorisation), for “Asahi Calpis Wellness” to the end substitute “Asahi Biocycle Co., Ltd”;

(b)

in the third column (additive) and the fourth column (composition, etc.), for “Bacillus subtilis C-1302”, in each place, substitute Bacillus velezensis.

Modification of authorisation: selenised yeast Saccharomyces cerevisiae (CNCM I-3060), inactivated (identification number 3b810)6.

In Commission Implementing Regulation (EU) 2019/804 concerning the renewal of the authorisation of organic form of selenium produced by Saccharomyces cerevisiae CNCM I-3060 and of selenomethionine produced by Saccharomyces cerevisiae NCYC R397 as feed additives for all animal species, etc.10, in the Annex, the entry for “3b810” is amended as follows—

(a)

in the fourth column (composition, etc.), for the section headed “Additive composition” substitute—

“Preparation of organic selenium (Se) produced by Saccharomyces cerevisiae (CNCM I-3060) containing 2,000 to 3,500 mg Se/kg with the below components:

  • Organic selenium: 97% minimum of total selenium

  • Selenomethionine: 63% minimum of total selenium”;

(b)

in the ninth column (other provisions), after point 4 insert—

“5.

The dusting potential of the additive must ensure a maximum selenium exposure of 0.2 mg Se/m3”,

Changes of authorisation holder: amendment of Commission Implementing Regulation (EU) No887/2011 and Commission Implementing Regulations (EU) 2017/961 and 2020/13957.

(1)

In Commission Implementing Regulation (EU) No887/2011 concerning the authorisation of a preparation of Enterococcus faecium CECT 4515 as feed additive for chickens for fattening, etc.11, in the Annex, in the second column of both tables (name of the holder of authorisation), for “Evonik Nutrition & Care GmbH)”, substitute “Evonik Operations GmbH”.

(2)

In Commission Implementing Regulation (EU) 2017/961 concerning the authorisation of a preparation of Enterococcus faecium CECT 4515 as a feed additive for weaned piglets, and a new use in water for drinking for weaned piglets and chickens for fattening, etc.12, in Annex I, in the table, in the second column (name of the holder of authorisation), for “Evonik Nutrition & Care GmbH” substitute “Evonik Operations GmbH”.

(3)

In Commission Implementing Regulation (EU) 2020/1395 concerning the renewal of the authorisation of Bacillus amyloliquefaciens CECT 5940 as a feed additive for chickens for fattening, its authorisation for chickens reared for laying, etc.13, in the Annex, in the table, in the second column (name of the holder of authorisation), for “Evonik Nutrition & Care GmbH” substitute “Evonik Operations GmbH”.

Amendment of Commission Implementing Regulation (EU) 2016/10958.

In Commission Implementing Regulation (EU) 2016/1095 concerning the authorisation of zinc acetate dihydrate, zinc chloride anhydrous, zinc oxide, zinc sulphate heptahydrate, zinc sulphate monohydrate, zinc chelate of amino acids hydrate, zinc chelate of protein hydrolysates, zinc chelate of glycine hydrate (solid) and zinc chelate of glycine hydrate (liquid) as feed additives for all animal species, etc.14, omit Article 4.

Amendment of Commission Implementing Regulation (EU) 2018/10399.

In Commission Implementing Regulation (EU) 2018/1039 concerning the authorisation of copper(II) diacetate monohydrate, copper(II) carbonate dihydroxy monohydrate, copper(II) chloride dihydrate, copper(II) oxide, copper(II) sulphate pentahydrate, copper(II) chelate of amino acids hydrate, copper(II) chelate of protein hydrolysates, copper(II) chelate of glycine hydrate (solid) and copper(II) chelate of glycine hydrate (liquid) as feed additives for all animal species, etc.15, omit Article 5.

Part 5Transitional Provisions

Transitional provision: a preparation of Bacillus velezensis (DSM 15544) (identification number 4b1820)10.

(1)

Any substance or product labelled “Bacillus subtilis C-3102 (DSM 15544)” or as containing “Bacillus subtilis C-3102 (DSM 15544)”, but otherwise produced and labelled in accordance with an authorisation contained in an instrument mentioned in regulation 5, may continue to be placed on the market and used under that authorisation.

(2)

Stocks of the relevant feed additive, and premixtures containing it, which are produced and labelled before the end of 19th June 2025 in accordance with the conditions of the prior authorisation and the labelling requirements applicable immediately before 20th December 2024, may continue to be placed on the market and used until they are exhausted.

(3)

Stocks of feed materials and compound feed containing the relevant feed additive, intended for food-producing animals, which are produced and labelled before the end of 19th December 2025 in accordance with the conditions of the prior authorisation and the labelling requirements applicable immediately before 20th December 2024, may continue to be placed on the market and used until they are exhausted.

(4)

Stocks of feed materials and compound feed containing the relevant feed additive, intended for non-food-producing animals, which are produced and labelled before the end of 19th December 2026 in accordance with the conditions of the prior authorisation and the labelling requirements applicable immediately before 20th December 2024, may continue to be placed on the market and used until they are exhausted.

(5)

In this regulation—

relevant feed additive” means the feed additive of a preparation of Bacillus velezensis (DSM 15544), with the identification number 4b1820 authorised under the prior authorisation;

prior authorisation” means the authorisations contained in Commission Implementing Regulation (EU) 2016/897 concerning the authorisation of a preparation of Bacillus subtilis (C-3102) (DSM 1544) as a feed additive for laying hens and ornamental fish, etc., Commission Implementing Regulation (EU) 2017/2312 concerning the authorisation of a new use of the preparation of Bacillus subtilis C-3102 (DSM 15544) as a feed additive for sows, suckling piglets and dogs, etc., and Commission Implementing Regulation (EU) 2018/1081 concerning the authorisation of the preparation of Bacillus subtilis C-3102 (DSM 15544) as a feed additive for pigs for fattening, etc.16, as the Regulations had effect immediately before 20th December 2024.

Transitional provision: selenised yeast Saccharomyces cerevisiae (CNCM I-3060), inactivated (identification number 3b810)11.

(1)

Stocks of the relevant feed additive, and premixtures containing it, which are produced and labelled before the end of 19th June 2025 in accordance with the conditions of the prior authorisation and the labelling requirements applicable immediately before 20th December 2024, may continue to be placed on the market and used until they are exhausted.

(2)

Stocks of feed materials and compound feed containing the relevant feed additive, intended for food-producing animals, which are produced and labelled before the end of 19th December 2025 in accordance with the conditions of the prior authorisation and the labelling requirements applicable immediately before 20th December 2024, may continue to be placed on the market and used until they are exhausted.

(3)

Stocks of feed materials and compound feed containing the relevant feed additive, intended for non-food-producing animals, which are produced and labelled before the end of 19th December 2026 in accordance with the conditions of the prior authorisation and the labelling requirements applicable immediately before 20th December 2024, may continue to be placed on the market and used until they are exhausted.

(4)

In this regulation—

relevant feed additive” means the feed additive selenised yeast Saccharomyces cerevisiae (CNCM I-3060), inactivated, with the identification number 3b810 authorised under the prior authorisation;

prior authorisation” means the authorisation contained in Commission Implementing Regulation (EU) 2019/804 concerning the renewal of the authorisation of organic form selenium produced by Saccharomyces cerevisiae CNCM I-3060 and of selenomethionine produced by Saccharomyces cerevisiae NCYC R397 as feed additives for all animal species17.

Transitional provision: butylated hydroxyanisole (identification number 1b320)12.

(1)

Butylated hydroxyanisole (E 320) is authorised to be placed on the market, processed or used as a feed additive for cats only to the extent that it is covered by and meets the conditions of the authorisation contained in Schedule 11 to these Regulations18, and in consequence of that authorisation butylated hydroxyanisole (E 320) shall no longer be treated as an existing product under, and for the purposes of, Article 10 of Regulation (EC) No 1831/2003.

(2)

Stocks of butylated hydroxyanisole as a feed additive for cats, and premixtures containing it, which are produced and labelled before the end of 19th June 2025 in compliance with the conditions of the authorisation and the labelling requirements applicable before 20th December 2024, may continue to be placed on the market and used until they are exhausted.

(3)

Stocks of feed materials and compound feed containing butylated hydroxyanisole, intended for cats, which are produced and labelled before the end of 19th December 2026 in compliance with the conditions of the authorisation and the labelling requirements applicable immediately before 20th December 2024, may continue to be placed on the market and used until they are exhausted.

Transitional provision: 6-phytase (EC 3.1.3.26) (identification number 4a16)13.

(1)

Stocks of the relevant feed additive, and premixtures containing it, which are produced and labelled before the end of 19th June 2025 in accordance with the conditions of the prior authorisation and the labelling requirements applicable immediately before 20th December 2024, may continue to be placed on the market and used until they are exhausted.

(2)

Stocks of feed materials and compound feed containing the relevant feed additive, intended for food-producing animals, which are produced and labelled before the end of 19th June 2025 in accordance with the conditions of the prior authorisation and the labelling requirements applicable immediately before 20th December 2024, may continue to be placed on the market and used until they are exhausted.

(3)

In this regulation—

relevant feed additive” means the feed additive 6-phytase (EC 3.1.3.26), with the identification number 4a16 authorised under the prior authorisation;

prior authorisation” means the authorisation contained in Commission Implementing Regulation (EU) No98/201219, as it had effect immediately before 20th December 2024, concerning the authorisation of 6-phytase (EC 3.1.3.26) produced by Pichia pastoris (DSM 23036) as a feed additive for chickens and turkeys for fattening, chickens reared for laying, turkeys reared for breeding, laying hens, other avian species for fattening and laying, weaned piglets, pigs for fattening and sows (holder of authorisation Huvepharma AD)20.

Transitional provision: copper chelate of hydroxy analogue of methionine (identification number 3b410i)14.

(1)

Stocks of the relevant feed additive, and premixtures containing it, which are produced and labelled before the end of 19th June 2025 in accordance with the conditions of the prior authorisation and the labelling requirements applicable immediately before 20th December 2024, may continue to be placed on the market and used until they are exhausted.

(2)

Stocks of feed materials and compound feed containing the relevant feed additive, intended for food-producing animals, which are produced and labelled before the end of 19th December 2025 in accordance with the conditions of the prior authorisation and the labelling requirements applicable immediately before 20th December 2024, may continue to be placed on the market and used until they are exhausted.

(3)

Stocks of feed materials and compound feed containing the relevant feed additive, intended for non-food-producing animals, which are produced and labelled before the end of 19th December 2026 in accordance with the conditions of the prior authorisation and the labelling requirements applicable immediately before 20th December 2024, may continue to be placed on the market and used until they are exhausted.

(4)

In this regulation—

relevant feed additive” means copper chelate of hydroxy analogue of methionine, with the identification number 3b410i authorised under the prior authorisation;

prior authorisation” means the authorisation contained in Commission Regulation (EU) No 349/201021, as it had effect immediately before 20th December 2024, concerning the authorisation of copper chelate of hydroxy analogue of methionine as a feed additive for all animal species22.

Transitional provision: manganese chelate of hydroxy analogue of methionine (identification number 3b510)15.

(1)

Stocks of the relevant feed additive, and premixtures containing it, which are produced and labelled before the end of 19th June 2025 in accordance with the conditions of the prior authorisation and the labelling requirements applicable immediately before 20th December 2024, may continue to be placed on the market and used until they are exhausted.

(2)

Stocks of feed materials and compound feed containing the relevant feed additive, intended for food-producing animals, which are produced and labelled before the end of 19th December 2025 in accordance with the conditions of the prior authorisation and the labelling requirements applicable immediately before 20th December 2024, may continue to be placed on the market and used until they are exhausted.

(3)

Stocks of feed materials and compound feed containing the relevant feed additive, intended for non-food-producing animals, which are produced and labelled before the end of 19th December 2026 in accordance with the conditions of the prior authorisation and the labelling requirements applicable immediately before 20th December 2024, may continue to be placed on the market and used until they are exhausted.

(4)

In this regulation—

relevant feed additive” means manganese chelate of hydroxy analogue of methionine, with the identification number 3b510 authorised under the prior authorisation;

prior authorisation” means the authorisation contained in Commission Regulation (EU) No 350/201023, as it had effect immediately before 20th December 2024, concerning the authorisation of manganese chelate of hydroxy analogue of methionine as a feed additive for all animal species24.

Transitional provision: zinc chelate of hydroxy analogue of methionine (identification number 3b610)16.

(1)

Stocks of the relevant feed additive, and premixtures containing it, which are produced and labelled before the end of 19th June 2025 in accordance with the conditions of the prior authorisation and the labelling requirements applicable immediately before 20th December 2024, may continue to be placed on the market and used until they are exhausted.

(2)

Stocks of feed materials and compound feed containing the relevant feed additive, intended for food-producing animals, which are produced and labelled before the end of 19th December 2025 in accordance with the conditions of the prior authorisation and the labelling requirements applicable immediately before 20th December 2024, may continue to be placed on the market and used until they are exhausted.

(3)

Stocks of feed materials and compound feed containing the relevant feed additive, intended for non-food-producing animals, which are produced and labelled before the end of 19th December 2026 in accordance with the conditions of the prior authorisation and the labelling requirements applicable immediately before 20th December 2024, may continue to be placed on the market and used until they are exhausted.

(4)

In this regulation—

relevant feed additive” means zinc chelate of hydroxy analogue of methionine, with the identification number 3b610 authorised under the prior authorisation;

prior authorisation” means the authorisation contained in Commission Regulation (EU) No 335/201025, as it had effect immediately before 20th December 2024, concerning the authorisation of zinc chelate of hydroxy analogue of methionine as a feed additive for all animal species26.

Part 6Revocation of assimilated direct legislation

Revocation of assimilated direct legislation17.

(1)

The instruments in Part 1 of Schedule 21 are revoked subject to Part 5 of these Regulations.

(2)

The instruments in Part 2 of Schedule 21 are revoked.

Andrew Gwynne
Parliamentary Under-Secretary of State,
Department of Health and Social Care

Schedule 1Authorisation of a preparation of chromium chelate of DL-methionine (identification number GB4d0001) as a feed additive for dairy cows

Regulation 3

The preparation of chromium chelate of DL-methionine, belonging to the additive category ‘zootechnical additives’ and to the functional group ‘other zootechnical’, is authorised as an additive in animal nutrition, in accordance with the specifications in the following table.

Additive

Chromium chelate of DL-methionine

Identification number

GB4d0001

Authorisation holder

Zinpro Animal Nutrition (Europe), Inc

Additive category

Zootechnical additives

Functional group

Other zootechnical

Additive composition

Solid preparation of chelates of chromium (Cr) with DL-methionine with the below components:

  • Calcium carbonate: 95.6%

  • Chromium-DL-Methionine: 3.4%

  • Vegetable oil:1.0%

Characterisation of the active substance

Chromium chelate of DL-methionine ([CH3S(CH2)2CH(NH2)COO]3 Cr)

Analytical method27

For the quantification of chromium in the feed additive:

  • inductively coupled plasma mass spectrometry (ICP-MS) in accordance with European standard BS EN 17053:201828

For the quantification of methionine in the feed additive:

  • ion-exchange chromatography coupled to post-column derivatisation and photometric detection (IEC-VIS) in accordance with BS EN ISO 13903:200529

For proving the chelated structure of the feed additive:

  • mid-infrared (IR) spectrometry together with the determination of the content of chromium and methionine in the feed additive

Species or category of animal

Dairy cows

Maximum age

Not applicable

Content of chromium in complete feed with a moisture content of 12%

Minimum content

0.2 mg/kg

Maximum content

0.5 mg/kg

Other provisions

The storage conditions and stability to heat treatment must be stated in the directions for use of the feed additive and premixture.

Schedule 2Renewal of authorisation of a preparation of Saccharomyces cerevisiae (MUCL 39885) (identification number 4b1710) as a feed additive for weaned piglets, and its authorisation extending to the use for cats, dogs and all Suidae other than sows and suckling piglets

Regulation 3

The preparation of Saccharomyces cerevisiae (MUCL 39885), belonging to the additive category ‘zootechnical additives’ and to the functional group ‘gut flora stabilisers’, is authorised as an additive in animal nutrition, in accordance with the specifications in the following table30.

Additive

Saccharomyces cerevisiae (MUCL 39885)

Identification number

4b1710

Authorisation holder

Prosol S.p.A.

Additive category

Zootechnical additives

Functional group

Gut flora stabilisers

Additive composition

Solid preparation of Saccharomyces cerevisiae (MUCL 39885) containing a minimum of 1 x 109 Colony Forming Units (CFU)/g

Characterisation of the active substance

Viable cells of Saccharomyces cerevisiae (MUCL 39885)

Analytical method31

For enumeration:

  • Pour plate method CGYE (chloramphenicol, glucose, yeast extract) agar in accordance with BS EN 15789:202132

For identification of the yeast strain:

  • Polymerase chain reaction (PCR) method in accordance with DD CEN/TS15790:200833

Species or category of animal

  • All Suidae other than suckling piglets or sows

  • Cats

  • Dogs

Maximum age

Not applicable

Colony Forming Units (CFU) of additive/kg complete feed with a moisture content of 12%

Minimum content

  • For all Suidae (other than suckling piglets, sows and Suidae for reproduction) 3 x 109 CFU/kg

  • For all Suidae for reproduction purposes other than sows: 6.4 x 109 CFU/kg

  • For cats and dogs: 7 x 1010 CFU/kg

Maximum content

No maximum

Other provisions

In the directions for use of the additive and premixtures, the storage conditions must be indicated.

Schedule 3Authorisation of a preparation of Pediococcus acidilactici (CNCM I-4622) (identification number 4d1712) as a feed additive for all animal species

Regulation 3

The preparation of Pediococcus acidilactici (CNCM I-4622), belonging to the additive category ‘technological’ and to the functional groups of ‘acidity regulator’ and ‘hygiene condition enhancer’, is authorised as an additive in animal nutrition, in accordance with the specifications in the following table.

Additive

Pediococcus acidilactici (CNCM I-4622)

Identification number

4d1712

Authorisation holder34

None

Additive category

Technological

Functional groups

Acidity regulator and hygiene condition enhancer

Additive composition

Solid preparation of Pediococcus acidilactici (CNCM I-4622) containing a minimum of 1x1010 Colony Forming Units (CFU)/g

Characterisation of the active substance(s)

Viable cells of Pediococcus acidilactici (CNCM I-4622)

Analytical method 35

For enumeration (colony count) of the feed additive:

  • Spread plate method using MRS agar in accordance with BS EN 15786:202136

For identification of the bacterial strain:

  • Pulsed-Field Gel Electrophoresis (PFGE)

Species or category of animal

All animal species

Maximum age

Not applicable

Colony Forming Units (CFU) of additive/kg of complete feed with a moisture content of 12%

Minimum content

1x109 CFU/kg

Maximum content

No maximum

Other provisions

1.

The storage conditions and stability to heat treatment must be stated in the directions for use of the feed additive and premixture.

2.

To be used only in mash compound feed intended for preparation of liquid feed on farm, or solid feed materials intended for preparation of liquid feed on farm.

3.

If Pediococcus acidilactici (CNCM I-4622) is to be used in feed containing coccidiostats, this feed additive is authorised for use with the following coccidiostats only, and in accordance with their individual authorisation criteria: decoquinate, diclazuril, halofuginone, nicarbazin, robenidine hydrochloride

Schedule 4Renewal of authorisation (with modification) of a preparation of monensin sodium produced by fermentation with Streptomyces cinnamonensis 28682 (NBIMCC 3419) (carrier: perlite, calcium carbonate) (identification number 51701) as a feed additive for chickens for fattening, chickens reared for laying and turkeys for fattening, and its authorisation extending to the use for turkeys reared for breeding

Regulation 3

The preparation of monensin sodium produced by fermentation with Streptomyces cinnamonensis 28682 (NBIMCC 3419) (carrier: perlite, calcium carbonate), belonging to the additive category ‘coccidiostats and histomonostats’, is authorised as an additive in animal nutrition, in accordance with the specifications in the following table37.

Additive

Monensin sodium

Identification number

51701

Authorisation holder

Huvepharma NV

Additive category

Coccidiostats and histomonostats

Functional group

No separate functional groups

Additive composition

Preparation of monensin sodium produced by fermentation with Streptomyces cinnamonensis 28682 (NBIMCC 3419) in powder form with the below components:

  • Monensin sodium technical substance: 250 g/kg containing:

    • Monensin A: 90% minimum

    • Monensin A + B: 95% minimum

    • Monensin C: 0.2% – 0.3%

  • Perlite: 150 – 200 g/kg

  • Calcium carbonate: 550 – 600 g/kg

Characterisation of the active substance(s)

Monensin sodium technical substance produced by fermentation with Streptomyces cinnamonensis 28682 (NBIMCC 3419)

  • Monensin sodium A (C36H61NaO11)

  • Monensin sodium B (C35H59NaO11)

  • Monensin sodium C (C37H63NaO11)

  • CAS no: 22373-78-038
Analytical method39

For the quantification of monensin in the feed additive, premixtures and compound feed:

  • Reversed phase high performance liquid chromatography using post-column derivatisation coupled to spectrophotometric detection (RP-HPLC-PCD-UV-Vis) in accordance with BS EN ISO 14183:200840

For the quantification of monensin sodium in chicken and turkey tissues:

  • Reversed phase high performance liquid chromatography coupled to a triple quadrupole mass spectrometer (RP-HPLC-MS/MS) or any equivalent methods

Species or category of animal

  • Chickens for fattening

  • Chickens reared for laying

  • Turkeys for fattening

  • Turkeys reared for breeding

Maximum age

  • Chickens for fattening: none

  • Chickens reared for laying, turkeys for fattening and turkeys reared for breeding: 16 weeks

Content of monensin (mg/kg of complete feed with a moisture content of 12%)

Minimum content

  • Chickens for fattening and chickens reared for laying: 100 mg/kg

  • Turkeys for fattening and turkeys reared for breeding: 60 mg/kg

Maximum content

  • Chickens for fattening and chickens reared for laying: 125 mg/kg

  • Turkeys for fattening and turkeys reared for breeding: 100 mg/kg

Maximum residue limits (MRLs) of monensin sodium in food of animal origin

  • Wet skin and fat: 25 µg/kg

  • Wet liver, wet kidney, and wet muscle: 8 µg/kg

Other provisions

1.

The storage conditions and stability to heat treatment must be stated in the directions for use of the feed additive and premixture.

2.

The additive must be incorporated in compound feed in the form of a premixture.

3.

Monensin sodium must not be mixed with other coccidiostats.

4.

Declaration to be made in the directions for use: “Dangerous for equines. This feed contains an ionophore. Avoid simultaneous administration with tiamulin and monitor for possible adverse reactions when used concurrently with other medicinal substances”.

5.

A post-market monitoring programme must be carried out by the holder of the authorisation for resistance to bacteria and Eimeria spp. A report containing the outcome of the post-market monitoring programme must be submitted to the appropriate authority41 by 19th December 2033.

Schedule 5Renewal of authorisation (with modification) of a preparation of monensin sodium produced by fermentation with Streptomyces cinnamonensis 28682 (NBIMCC 3419) (carrier: perlite, wheat bran) (identification number 51701) as a feed additive for chickens for fattening, turkeys for fattening and its authorisation extending to the use for chickens reared for laying and turkeys reared for breeding

Regulation 3

The preparation of monensin sodium produced by fermentation with Streptomyces cinnamonensis 28682 (NBIMCC 3419) (carrier: perlite, wheat bran), belonging to the additive category ‘coccidiostats and histomonostats’, is authorised as an additive in animal nutrition, in accordance with the specifications in the following table42.

Additive

Monensin sodium

Identification number

51701

Authorisation holder

Huvepharma NV

Additive category

Coccidiostats and histomonostats

Functional group

No separate functional groups

Additive composition

Preparation of monensin sodium produced by fermentation with Streptomyces cinnamonensis 28682 (NBIMCC 3419) in powder form with the below components:

  • Monensin sodium technical substance: 250 g/kg containing:

    • Monensin A: 90% minimum

    • Monensin A + B: 95% minimum

    • Monensin C: 0.2% – 0.3%

  • Perlite: 150 – 200 g/kg

  • Wheat bran: 550 – 600 g/kg

Characterisation of the active substance(s)

Monensin sodium technical substance produced by fermentation with Streptomyces cinnamonensis 28682 (NBIMCC 3419)

  • Monensin sodium A (C36H61NaO11)

  • Monensin sodium B (C35H59NaO11)

  • Monensin sodium C (C37H63NaO11)

  • CAS no: 22373-78-043
Analytical method44

For the quantification of monensin in the feed additive, premixtures and compound feed:

  • Reversed phase high performance liquid chromatography using post-column derivatisation coupled to spectrophotometric detection (RP-HPLC-PCD-UV-Vis) in accordance with BS EN ISO 14183:200845

For the quantification of monensin sodium in chicken and turkey tissues:

  • Reversed phase high performance liquid chromatography coupled to a triple quadrupole mass spectrometer (RP-HPLC-MS/MS) or any equivalent methods

Species or category of animal

  • Chickens for fattening

  • Chickens reared for laying

  • Turkeys for fattening

  • Turkeys reared for breeding

Maximum age

  • Chickens for fattening: None

  • Chickens reared for laying, turkeys for fattening and turkeys reared for breeding: 16 weeks

Content of monensin (mg/kg of complete feed with a moisture content of 12%)

Minimum content

  • Chickens for fattening and chickens reared for laying: 100 mg/kg

  • Turkeys for fattening and turkeys reared for breeding: 60 mg/kg

Maximum content

  • Chickens for fattening and chickens reared for laying: 125 mg/kg

  • Turkeys for fattening and turkeys reared for breeding: 100 mg/kg

Maximum residue limits (MRLs) of monensin sodium in food of animal origin

  • Wet skin and fat: 25 µg/kg

  • Wet liver, wet kidney, and wet muscle: 8 µg/kg

Other provisions

1.

The storage conditions and stability to heat treatment must be stated in the directions for use of the feed additive and premixture.

2.

The additive must be incorporated in compound feed in the form of a premixture.

3.

Monensin sodium must not be mixed with other coccidiostats.

4.

Declaration to be made in the directions for use: “Dangerous for equines. This feed contains an ionophore. Avoid simultaneous administration with tiamulin and monitor for possible adverse reactions when use concurrently with other medicinal substances”.

5.

A post-market monitoring programme must be carried out by the holder of the authorisation for resistance to bacteria and Eimeria spp. A report containing the outcome of the post-market monitoring programme must be submitted to the appropriate authority by 19th December 2033.

Schedule 6Renewal of authorisation (with modification) of a preparation of 6-phytase (EC 3.1.3.26) produced by fermentation with Komagataella phaffii (formerly Komagataella pastoris) (DSM 23036) (identification number 4a16) as a feed additive for chickens for fattening, chickens reared for laying, laying hens, turkeys for fattening, turkeys reared for breeding, other avian species for fattening and laying, sows, pigs for fattening and weaned piglets, and its authorisation extending to the use for all avian species and all Suidae

Regulation 3

The preparation of 6-phytase (EC 3.1.3.26) produced by fermentation with Komagataella phaffii (formerly Komagataella pastoris) (DSM 23036), belonging to the additive category ‘zootechnical’ and to the functional group ‘digestibility enhancers’, is authorised as an additive in animal nutrition, in accordance with the specifications in the following table46.

Additive

6-phytase (EC 3.1.3.26)

Identification number

4a16

Authorisation holder

Huvepharma NV

Additive category

Zootechnical additives

Functional group

Digestibility enhancers

Additive composition

Preparation of 6-phytase (EC 3.1.3.26) produced by fermentation with Komagataella phaffii (DSM 23036) having a minimum enzyme activity of 4,000 OTU/g in solid form and 8,000 OTU/g in liquid form47

Characterisation of the active substance(s)

6-phytase (EC 3.1.3.26) produced by fermentation with Komagataella phaffii (DSM 23036)

  • CAS no: 9001-89-248
  • EC (IUBMB) no: 3.1.3.2649
Analytical method50

For the quantification of phytase activity in the feed additive, premixtures and compound feed:

  • Colorimetric method based on the quantification of the inorganic phosphate released by the enzyme from the sodium phytate

Species or category of animal

  • All avian species

  • All Suidae

Maximum age

Not applicable

Content of 6-phytase (EC 3.1.3.26) (units of activity (OTU)/kg of complete feed with a moisture content of 12%)

Minimum content

  • All avian species other than turkeys and all Suidae other than piglets: 125 OTU/kg

  • Turkeys and piglets: 250 OTU/kg

Maximum content

No maximum level

Other provisions

The storage conditions and stability to heat treatment must be stated in the directions for use of the feed additive and premixture.

Schedule 7Renewal of authorisation (with modification) of a preparation of Bacillus velezensis (formerly Bacillus subtilis) (DSM 15544) (identification number 4b1820) as a feed additive for weaned piglets, chickens reared for laying, turkeys, minor avian species, ornamental birds and game birds; consolidation of existing authorised uses for laying hens and chickens for fattening; and its authorisation as a feed additive extending existing authorised uses to cover all other avian species

Regulation 3

The preparation of Bacillus velezensis (formerly Bacillus subtilis) (DSM 15544), belonging to the additive category ‘zootechnical’ and to the functional group ‘gut flora stabilisers’, is authorised as an additive in animal nutrition, in accordance with the specifications in the following table51.

Additive

Bacillus velezensis (DSM 15544)

Identification number

4b1820

Authorisation holder

Asahi Biocycle Co., Ltd

Additive category

Zootechnical additives

Functional group

Gut flora stabilisers

Additive composition

Solid preparation of Bacillus velezensis (DSM 15544) containing a minimum of 1x1010 Colony Forming Units (CFU)/g

Characterisation of the active substance(s)

Viable spores of Bacillus velezensis (DSM 15544)

Analytical method52

For enumeration (colony count) of the feed additive:

  • Spread plate method using tryptone soya agar in all target matrices in accordance with BS EN 15784:202153

For identification of the feed additive:

  • Pulsed-field gel electrophoresis (PFGE)

Species or category of animal

  • Weaned piglets

  • All avian species

Maximum age

Not applicable

Colony Forming Units (CFU)/kg of complete feed with a moisture content of 12%

Minimum content

3x10 8 CFU/kg

Maximum content

No maximum level

Other provisions

The storage conditions and stability to heat treatment must be stated in the directions for use of the feed additive and premixture.

Schedule 8Authorisation of a preparation of L-histidine monohydrochloride monohydrate produced by fermentation with Escherichia coli K-12 (KCCM 80212) (identification number 3c352i) as a feed additive for all animal species

Regulation 3

The preparation of L-histidine monohydrochloride monohydrate produced by fermentation with Escherichia coli K-12 (KCCM 80210), belonging to the additive category ‘nutritional additives’ and to the functional group ‘amino acids, their salts and analogues’, is authorised as an additive in animal nutrition, in accordance with the specifications in the following table.

Additive

L-histidine monohydrochloride monohydrate

Identification number

3c352i

Authorisation holder54

None

Additive category

Nutritional additives

Functional group

Amino acids, their salts and analogues

Additive composition

L-histidine monohydrochloride monohydrate with a purity criteria not less than 98% as a powder with the following components:

  • Moisture: 1% maximum

  • Histidine: 72% minimum

  • Histamine: 100ppm maximum

Characterisation of the active substance(s)

L-histidine monohydrochloride monohydrate produced by fermentation with Escherichia coli K-12 (KCCM 80212) (C6H12ClN3O3)

  • CAS no: 5934-29-255
  • EINECS no: 611-821-456
Analytical method57

For the quantification of histidine in the feed additive:

  • High performance liquid chromatography coupled with photometric detection (HPLC-UV) in accordance with BS EN ISO 13903:200558; or
  • Ion-exchange chromatography coupled with post-column derivatisation and optical detection (IEC-VIS/FLD)

For the quantification of histidine in premixtures, feed materials and compound feed:

  • Ion-exchange chromatography coupled to post-column derivatisation and photometric detection (IEC-VIS), Commission Regulation (EC) 152/2009 (Annex III, F)

For the quantification of histamine in the feed additive:

  • High performance liquid chromatography coupled with photometric detection (HPLC-UV) in accordance with BS EN ISO 13903:2005

Species or category of animal

All animal species

Maximum age

Not applicable

Content of L-histidine monohydrochloride monohydrate (mg/kg of complete feed with a moisture content of 12%)

Minimum content

No minimum

Maximum content

No maximum

Other provisions

1.

The storage conditions and stability to heat treatment must be stated in the directions for use of the feed additive and premixture.

2.

L-histidine monohydrochloride monohydrate may be placed on the market and used as an additive consisting of a preparation.

3.

The histidine content must be indicated on the label of the additive and premixture and must contain the following declaration on the label of the additive and the premixture:

“The supplementation with L-histidine monohydrochloride monohydrate shall be limited to the nutritional requirements of the target animal, which depend on the species, the physiological state of the animal, the performance level, the environmental conditions, the level of other amino acids in the diet and the level of essential trace elements such as copper and zinc”.

4.

The endotoxin content of the additive and its dusting potential must ensure a maximal endotoxin exposure of 1600 IU endotoxins/m3 air59.

Schedule 9Authorisation of a preparation of L-tryptophan produced by fermentation with Escherichia coli (KCCM 80210) (identification number 3c440i) as a feed additive for all animal species

Regulation 3

The preparation of L-tryptophan produced by fermentation with Escherichia coli (KCCM 80210), belonging to the additive category ‘nutritional additives’ and to the functional group ‘amino acids, their salts and analogues’, is authorised as an additive in animal nutrition, in accordance with the specifications in the following table.

Additive

L-tryptophan

Identification number

3c440i

Authorisation holder60

None

Additive category

Nutritional additives

Functional group

Amino acids, their salts and analogues

Additive composition

L-tryptophan with a purity criteria on a dry matter basis not less than 98% as a powder with the following components:

  • Moisture content: 1% maximum

  • 1,1’-ethylidene-bis-L-tryptophan: 10 mg/kg maximum

Characterisation of active substance(s)

L-tryptophan produced by fermentation with Escherichia coli (KCCM 80210) (C11H12N2O2)

  • CAS no: 73-22-361
  • EINECS no: 200-795-662
Analytical method63

For the identification of L-tryptophan in the feed additive:

• Food Chemical Codex “L-tryptophan monograph”64

For the determination of tryptophan in the feed additive and premixtures:

  • High performance liquid chromatography with fluorescence detection (HPLC-FLD) in accordance with BS EN ISO 13904:201665

For the determination of tryptophan in feed materials and compound feed:

  • High performance liquid chromatography with fluorescence detection (HPLC-FLD) in accordance with Commission Regulation (EC) 152/2009 (Annex III, G)

Species or category of animal

All animal species

Maximum age

Not applicable

Content of L-tryptophan (mg/kg of complete feed with a moisture content of 12%)

Minimum content

No minimum

Maximum content

No maximum

Other provisions

1.

L-tryptophan must be rumen protected when administered to ruminants.

2.

Declaration to be made on the label of the additive and premixture: “The supplementation with L-tryptophan shall take into account all essential and conditionally essential amino acids in order to avoid imbalances”.

3.

The endotoxin content of the additive and its dusting potential must ensure a maximal endotoxin exposure of 1600 IU endotoxins/m3 air66.

Schedule 10Authorisation of a preparation of L-lysine sulphate produced by fermentation with Corynebacterium glutamicum (KCCM 80227) (identification number 3c324i) as a feed additive for all animal species

Regulation 3

The preparation of L-lysine sulphate produced by fermentation with Corynebacterium glutamicum (KCCM 80227), belonging to the additive category ‘nutritional additives’ and to the functional group ‘amino acids, their salts and analogues’, is authorised as an additive in animal nutrition, in accordance with the specifications in the following table.

Additive

L-lysine sulphate

Identification number

3c324i

Authorisation holder67

None

Additive category

Nutritional additives

Functional group

Amino acids, their salts and analogues

Additive composition

Granulated preparation of L-lysine sulphate with a minimum of 52% L-lysine, a maximum of 24% sulphate and a maximum moisture content of 4%

Characterisation of the active substance(s)

L-lysine sulphate produced by fermentation with Corynebacterium glutamicum (KCCM 80227) (C12H28N4O4· H2SO4)

  • CAS no: 60343-69-368
Analytical method69

For the quantification of lysine in the feed additive and premixtures containing more than 10% lysine:

  • •on exchange chromatography coupled with post-column derivatisation and optical detection (IEC-VIS/FLD) in accordance with BS EN ISO 17180:201370

For the identification of sulphate in the feed additive:

  • European Pharmacopoeia Monograph 2030171

For quantification of lysine in premixtures, feed materials and compound feed:

  • •on-exchange chromatography coupled with post-column derivatisation and optical detection (IEC-VIS) in accordance with Commission Regulation (EC) 152/2009 (Annex III, F)

For the quantification of lysine in water:

  • Ion exchange chromatography coupled with post-column derivatisation and optical detection (IEC-VIS/FLD) in accordance with BS EN ISO 17180:2013

Species or category of animal

All animal species

Maximum age

Not applicable

Content of L-lysine sulphate (mg/kg of complete feed with a moisture content of 12%)

Minimum content

No minimum

Maximum content

10,000 mg/kg

Other provisions

1.

The storage conditions and stability to heat treatment must be stated in the directions for use of the feed additive and premixture.

2.

The L-lysine content must be stated on the labelling of the additive.

3.

Declaration to be made on the label of the additive and premixture: “The supplementation with L-lysine should take into account all essential and conditionally essential amino acids in order to avoid imbalances”.

Schedule 11Authorisation of the substance butylated hydroxyanisole (identification number 1b320) as a feed additive for cats

Regulation 3

The substance butylated hydroxyanisole, belonging to the additive category ‘technological feed additive’ and to the functional group ‘antioxidants’, is authorised as an additive in animal nutrition, in accordance with the specifications in the following table72.

Additive

Butylated hydroxyanisole

Identification number

1b320

Authorisation holder73

None

Additive category

Technological

Functional group

Antioxidants

Additive composition

Butylated hydroxyanisole with a minimum content of 98.5% in a waxy solid form

Characterisation of the active substance(s)

Butylated hydroxyanisole containing a mixture of 2-tert-butyl-4-hydroxyanisole and a minimum of 85% 3-tert-butyl-4-hydroxyanisole (C11H16O2)

  • CAS no: 25013-16-574
Analytical method75

For the quantification of butylated hydroxyanisole in feed additives:

  • Gas chromatography coupled to flame ionization detection (GC-FID) (Food Chemical Codex 7th edition method)76

For the quantification of butylated hydroxyanisole in premixtures and compound feed:

  • Reversed phase high performance liquid chromatography coupled to ultraviolet-diode-array detection (RP-HPLC-UV-DAD, 285 nm)

Species or category of animal

Cats

Maximum age

Not applicable

Content of butylated hydroxyanisole (mg/kg of complete feed with a moisture content of 12%)

Minimum content

No minimum

Maximum content

150 mg/kg

Other provisions

1.

The storage conditions and stability to heat treatment must be stated in the directions for use of the feed additive and premixture.

2.

Butylated hydroxyanisole is authorised to be used in combination with butylated hydroxytoluene up to a maximum combined content of 150 mg/kg of complete feed.

Schedule 12Authorisation of a preparation of L-lysine base (liquid) produced by fermentation with Corynebacterium glutamicum (KCCM 80183) (identification number 3c320) as a feed additive for all animal species

Regulation 3

The preparation of L-lysine base (liquid) produced by fermentation with Corynebacterium glutamicum (KCCM 80183), belonging to the additive category ‘nutritional additives’ and to the functional group ‘amino acids, their salts and analogues’, is authorised as an additive in animal nutrition, in accordance with the specifications in the following table.

Additive

L-lysine base (liquid)

Identification number

3c320

Authorisation holder77

None

Additive category

Nutritional additives

Functional group

Amino acids, their salts and analogues

Additive composition

Aqueous solution with a minimum of 50% L-lysine

Characterisation of the active substance(s)

L-lysine base (liquid) (NH2(CH2)CH(NH2)COOH) produced by fermentation with Corynebacterium glutamicum (KCCM 80183)

  • CAS no: 56-87-178
Analytical method79

For the quantification of lysine in the feed additive and premixtures containing more than 10% lysine:

  • Ion-exchange chromatography coupled with post-column derivatisation and optical detection (IEC-VIS/FLD) in accordance with BS EN ISO 17180:201380

For quantification of lysine in premixtures, feed materials and compound feed:

  • Ion-exchange chromatography coupled with post-column derivatisation and optical detection (IEC-VIS) in accordance with Commission Regulation (EC) 152/2009 (Annex III, F)

For the quantification of lysine in water:

  • Ion exchange chromatography coupled with post-column derivatisation and optical detection (IEC-VIS/FLD) in accordance with BS EN ISO 17180:2013; or

  • Ion exchange chromatography coupled with post-column derivatisation and optical detection (IEC-VIS) in accordance with Commission Regulation (EC) 152/2009 (Annex III, F)

Species or category of animal

All animal species

Maximum age

Not applicable

Content of L-lysine (mg/kg of complete feed with a moisture content of 12%)

Minimum content

No minimum

Maximum content

No maximum

Other provisions

1.

The L-lysine content must be stated on the labelling of the additive.

2.

The additive may be used via water for drinking.

3.

Declaration to be made on the label of the additive and premixture: “The supplementation with L-lysine, in particular via water for drinking, should take into account all essential and conditionally essential amino acids in order to avoid imbalances”.

Schedule 13Authorisation of the substance L-lysine monohydrochloride (technically pure) produced by fermentation with Corynebacterium glutamicum (KCCM 80183) (identification number 3c322ii) as a feed additive for all animal species

Regulation 3

The substance L-lysine monohydrochloride (technically pure) produced by fermentation with Corynebacterium glutamicum (KCCM 80183), belonging to the additive category ‘nutritional additives’ and to the functional group ‘amino acids, their salts and analogues’, is authorised as an additive in animal nutrition, in accordance with the specifications in the following table.

Additive

L-lysine monohydrochloride (technically pure)

Identification number

3c322ii

Authorisation holder81

None

Additive category

Nutritional additives

Functional group

Amino acids, theirs salts and analogues

Additive composition

Powder of L-lysine monohydrochloride with a minimum of 78% L-lysine and a maximum moisture content of 1.5%

Characterisation of the active substance(s)

L-lysine monohydrochloride (technically pure)

(NH2(CH2)4CH(NH2)COOH) produced by fermentation with Corynebacterium glutamicum (KCCM 80183)

  • CAS no: 657-27-282
Analytical method83

For the identification of L-lysine monohydrochloride in the feed additive:

  • Food Chemicals Codex “L-lysine monohydrochloride monograph”84

For the quantification of lysine in the feed additive and premixtures containing more than 10% lysine:

  • Ion-exchange chromatography coupled with post-column derivatisation and optical detection (IEC-VIS/FLD) in accordance with BS EN ISO 17180:201385

For the quantification of lysine in premixtures, feed materials and compound feed:

  • Ion-exchange chromatography coupled with post-column derivatisation and optical detection (IEC-VIS) in accordance with Commission Regulation (EC) 152/2009 (Annex III, F)

For the quantification of lysine in water:

  • Ion exchange chromatography coupled with post-column derivatisation and optical detection (IEC-VIS/FLD) in accordance with BS EN ISO 17180:2013; or

  • Ion exchange chromatography coupled with post-column derivatisation and optical detection (IEC-VIS) in accordance with Commission Regulation (EC) 152/2009 (Annex III, F)

Species or category of animal

All animal species

Maximum age

Not applicable

Content of L-lysine monohydrochloride (mg/kg of complete feed with a moisture content of 12%)

Minimum content

No minimum

Maximum content

No maximum

Other provisions

1.

The L-lysine content must be stated on the labelling of the additive.

2.

The additive may be used via water for drinking.

3.

Declaration to be made on the label of the additive and the premixture: “The supplementation with L-lysine, in particular via water for drinking, should take into account all essential and conditionally essential amino acids in order to avoid imbalances.”

Schedule 14Authorisation of the substance disodium 5’ -guanylate (GMP) produced by fermentation with Corynebacterium stationis (KCCM 10530) and Escherichia coli K-12 (KFCC 11067) (identification number 2b627i) as a feed additive for all animal species

Regulation 3

The substance disodium 5’ -guanylate (GMP) produced by fermentation with Corynebacterium stationis (KCCM 10530) and Escherichia coli K-12 (KFCC 11067), belonging to the additive category ‘sensory’ and to the functional group ‘flavouring compounds’, is authorised as an additive in animal nutrition, in accordance with the specifications in the following table.

Additive

Disodium 5’ -guanylate

Identification number

2b627i

Authorisation holder86

None

Additive category

Sensory

Functional group

Flavouring compounds

Additive composition

Powder of disodium 5’ -guanylate with a minimum purity criteria of 97%

Characterisation of the active substance(s)

Hydrated form of disodium 5’ -guanylate (GMP) produced by fermentation with Corynebacterium stationis (KCCM 10530) and Escherichia coli K-12 (KFCC 11067) (C10H12N5Na2O8P)

  • CAS no: 5550-12-987
  • EINECS no: 226-914-188
Analytical method89

For the identification of disodium 5’ -guanylate (GMP) in the feed additive:

  • FAO JECFA monograph “disodium 5’-guanylate”90

For the determination of disodium 5’ -guanylate (GMP) in the feed additive, flavouring premixtures and water:

  • High performance liquid chromatography coupled to UV detection (HPLC-UV)

Species or category of animal

All animal species

Maximum age

Not applicable

Content of disodium 5’ -guanylate (mg/kg of complete feed with a moisture content of 12%)

Minimum content

No minimum

Maximum content

No maximum

Other provisions

1.

The storage conditions and stability to heat treatment must be stated in the directions for use of the feed additive and premixture.

2.

The additive must be incorporated into the feed in the form of a premixture.

3.

On the label of the additive the following must be indicated: ‘Recommended maximum content of the active substance when used alone or in combination with other ribonucleotides up to the same level per kg of complete feedingstuff with a moisture content of 12%: 50mg’.

4.

The functional group, identification number, name and added amount of the active substance must be indicated on the label of the premixture where the use level on the label of the premixture would result in the level of the active substance (alone or in combination with other ribonucleotides) in complete feed exceeding 50mg/kg.

Schedule 15Authorisation of a preparation of muramidase (EC 3.2.1.17) produced by fermentation with Trichoderma reesei (DSM 32338) (identification number 4d16) as a feed additive for weaned piglets

Regulation 3

The preparation of muramidase (EC 3.2.1.17) produced by fermentation with Trichoderma reesei (DSM 32338), belonging to the additive category ‘zootechnical’ and to the functional group ‘other zootechnical’, is authorised as an additive in animal nutrition, in accordance with the specifications in the following table.

Additive

Muramidase (EC 3.2.1.17)

Identification number

4d16

Authorisation holder

DSM Nutritional Products Ltd

Additive category

Zootechnical

Functional group

Other zootechnical

Additive composition

Solid and liquid preparations of muramidase (EC 3.2.1.17) produced by fermentation with Trichoderma reesei (DSM 32338) having a minimum enzyme activity of 60,000 LSU(F)/g91

Characterisation of the active substance(s)

Muramidase (EC 3.2.1.17) produced by fermentation with Trichoderma reesei (DSM 32338):

  • CAS no: 9001-63-292
  • EINECS no: 232-620-493
  • EC (IUBMB) no: 3.2.1.17

Analytical method94

For the quantification of muramidase in the feed additive, premixtures and compound feed:

  • Fluorescence-based enzyme assay method that determines the enzyme-catalysed depolymerisation of a fluorescein-labelled peptidoglycan preparation at pH 6.0 and 30°C

Species or category of animal

Weaned piglets

Maximum age

Not applicable

Content of muramidase (units of activity/kg of complete feed with a moisture content of 12%)

Minimum content

50,000 LSU(F)/kg

Maximum content

65,000 LSU(F)/kg

Other provisions

The storage conditions and stability to heat treatment must be stated in the directions for use of the feed additive and premixture.

Schedule 16Authorisation of the substance of phytomenadione (Vitamin K1) (identification number 3a712) as a feed additive for horses

Regulation 3

The substance phytomenadione (Vitamin K1), belonging to the additive category ‘nutritional additives’ and to the functional group ‘vitamins, pro-vitamins and chemically well-defined substances having similar effect’, is authorised as an additive in animal nutrition, in accordance with the specifications in the following table.

Additive

Vitamin K 1 or phytomenadione

Identification number

3a712

Authorisation holder95

None

Additive category

Nutritional additives

Functional group

Vitamins, pro-vitamins and chemically well-defined substances having similar effect

Additive composition

Produced by chemical synthesis

  • Solid preparation containing a minimum of 4.2% of phytomenadione (Vitamin K1)

Characterisation of the active substance(s)

2-methyl-3-[(E-7R,11R)-3,7,11,15-tetramethylhexadec-2-enyl] naphthalene-1, 4-dione (phytomenadione) (C31H46O2)

  • CAS no: 84-80-096
  • EINECS no: 201-564-297

with the following components:

  • E-phytomenadione: 75% minimum

  • E-epoxyphytomenadione: 4% maximum

  • Total purity of E-phytomenadione, E-epoxyphytomenadione and Z-phytomenadione isomers: 97% minimum

Analytical method98

For the determination of phytomenadione (Vitamin K1) in the feed additive:

  • High performance liquid chromatography (HPLC) in accordance with the European Pharmacopoeia99

For the determination of phytomenadione in the additive preparation and in complimentary feed:

  • High performance liquid chromatography with fluorescence detection (HPLC-FLD) in accordance with BS EN 14148:2003100

Species or category of animal

Horses

Maximum age

Not applicable

Content of phytomenadione (Vitamin K1) (mg/kg of complete feed with a moisture content of 12%)

Minimum content

No minimum

Maximum content

No maximum

Other provisions

The storage conditions and stability to heat treatment must be stated in the directions for use of the feed additive and premixture.

Schedule 17Renewal of authorisation (with modification) of a preparation of copper chelate of hydroxy analogue of methionine (identification number 3b410i (formerly 3b4.10)) as a feed additive for all animal species

Regulation 3

The preparation of copper chelate of hydroxy analogue of methionine, belonging to the additive category ‘nutritional additives’ and to the functional group ‘compounds of trace elements’, is authorised as an additive in animal nutrition, in accordance with the specifications in the following table101.

Additive

Copper chelate of hydroxy analogue of methionine

Identification number

3b410i

Authorisation holder102

None

Additive category

Nutritional additives

Function group

Compounds of trace elements

Additive composition

Copper chelate of hydroxy analogue of methionine in solid form containing a minimum of 16% copper and the following components:

  • (2-hydroxy-4-methylthio) butanoic acid: 78% minimum

  • Nickel: 20 ppm maximum

Characterisation of the active substance(s)

Copper chelate of hydroxy analogue of methionine (Cu(CH3S(CH2)2-CH(OH)-COO)2)

  • CAS no: 292140-30-8103
Analytical method104

For the quantification of the hydroxy analogue of methionine content in the feed additive:

  • Titrimetry, potentiometric titration after oxidation reduction reaction

For the quantification of total copper in the feed additive:

  • Inductively coupled plasma atomic emission spectrometry, ICP-AES (BS EN 15510:2017105 or BS EN 15621:2017106); or
  • Atomic absorption spectrometry, AAS (BS EN ISO 6869:2001107)

For the quantification of total copper in premixtures:

  • Inductively coupled plasma atomic emission spectrometry, ICP-AES (BS EN 15510:2017 or BS EN 15621:2017); or

  • Atomic absorption spectrometry, AAS (BS EN ISO 6869:2001); or

  • Inductively coupled plasma mass spectrometry, ICP-MS (BS EN 17053:2018108)

For the quantification of total copper in feed materials and compound feed:

  • Inductively coupled plasma atomic emission spectrometry, ICP-AES (BS EN 15510:2017 or BS EN 15621:2017); or

  • Atomic absorption spectrometry, AAS (in accordance with Commission Regulation (EC) 152/2009 (Annex IV, C) or BS EN ISO 6869:2001); or

  • Inductively coupled plasma mass spectrometry, ICP-MS (BS EN 17053:2018)

Species or category of animal

All animal species

Maximum age

Not applicable

Content of copper (Cu) (mg/kg of complete feed with a moisture content of 12%)

Minimum content

No minimum

Maximum content

  • Bovines before the start of rumination and ovines: 15 mg/kg (total)

  • Other bovines: 30 mg/kg (total)

  • Caprines: 35 mg/kg (total)

  • Piglets

    • Suckling and weaned up to 4 weeks after weaning: 150 mg/kg (total)

    • From 5th week up to 8 weeks after weaning: 100 mg/kg (total)

  • Crustaceans: 50 mg/kg (total)

  • Other animal species: 25 mg/kg (total)

Other provisions

1.

The additive must be incorporated into feed in the form of a premixture.

2.

The following words must be included in the labelling:

  • for feed for sheep if the level of copper in the feed exceeds 10 mg/kg: ‘The level of copper in this feed may cause poisoning in certain breeds of sheep.’

  • for feed in bovines after the start of rumination if the level of copper in the feed is less than 20 mg/kg: ‘The level of copper in this feed may cause copper deficiencies in cattle grazing pastures with high contents of molybdenum or sulphur.’

Schedule 18Renewal of authorisation (with modification) of a preparation of manganese chelate of hydroxy analogue of methionine (identification number 3b510 (formerly 3b5.10)) as a feed additive for all animal species

Regulation 3

The preparation of manganese chelate of hydroxy analogue of methionine, belonging to the additive category ‘nutritional additives’ and to the functional group ‘compounds of trace elements’, is authorised as an additive in animal nutrition, in accordance with the specifications in the following table109.

Additive

Manganese chelate of hydroxy analogue of methionine

Identification number

3b510

Authorisation holder110

None

Additive category

Nutritional additives

Functional group

Compounds of trace elements

Additive composition

Manganese chelate of hydroxy analogue of methionine in solid form containing a minimum of 14% manganese and the following components:

  • (2-hydroxy-4-methylthio) butanoic acid: 76% minimum

  • Nickel: 170 ppm maximum

Characterisation of the active substance(s)

Manganese chelate of hydroxy analogue of methionine (Mn(CH3S(CH2)2-CH(OH)-COO)2)

  • CAS no: 292140-29-5111
Analytical method112

For the quantification of the hydroxy analogue of methionine content in the feed additive:

  • Titrimetry, potentiometric titration after oxidation reduction reaction

For the quantification of total manganese in the feed additive and premixtures:

  • Atomic absorption spectrometry, AAS (BS EN ISO 6869:2001113); or
  • Inductively coupled plasma atomic emission spectrometry, ICP-AES (BS EN 15510:2017114); or
  • Inductively coupled plasma atomic emission spectrometry after pressure digestion, ICO-AES (BS EN 15621:2017115)

For the quantification of total manganese in feed materials and compound feed:

  • Atomic absorption spectrometry, AAS (in accordance with Commission Regulation (EC) 152/2009 (Annex IV, C) or BS EN ISO 6869:2001); or

  • Inductively coupled plasma atomic emission spectrometry, ICP-AES (BS EN 15510:2017); or

  • Inductively coupled plasma atomic emission spectrometry after pressure digestion, ICP-AES (BS EN 15621:2017)

Species or category of animal

All animal species

Maximum age

Not applicable

Content of manganese (Mn) (mg/kg of complete feed with a moisture content of 12%)

Minimum content

No minimum

Maximum content

  • Fish: 100 mg/kg (total)

  • Other animal species: 150 mg/kg (total)

Other provisions

1.

The additive must be incorporated into feed in the form of a premixture.

2.

Manganese chelate of hydroxy analogue of methionine may be placed on the market and used as an additive consisting of a preparation.

Schedule 19Renewal of authorisation (with modification) of a preparation of zinc chelate of hydroxy analogue of methionine (identification number 3b610 (formerly 3b6.10)) as a feed additive for all animal species

Regulation 3

The preparation of zinc chelate of hydroxy analogue of methionine, belonging to the additive category ‘nutritional additives’ and to the functional group ‘compounds of trace elements’, is authorised as an additive in animal nutrition, in accordance with the specifications in the following table116.

Additive

Zinc chelate of hydroxy analogue of methionine

Identification number

3b610

Authorisation holder117

None

Additive category

Nutritional additives

Functional group

Compounds of trace elements

Additive composition

Zinc chelate of hydroxy analogue of methionine in solid form containing a minimum of 17% zinc and the following components:

  • (2-hydroxy-4-methylthio) butanoic acid: 79% minimum

  • Nickel: 1.7 ppm maximum

Characterisation of the active substance(s)

Zinc chelate of hydroxy analogue of methionine (Zn(CH3S(CH2)2-CH(OH)-COO)2)

  • CAS no: 292140-29-5118

Analytical method119

For the quantification of the hydroxy analogue of methionine content in the feed additive:

  • Titrimetry, potentiometric titration after oxidation reduction reaction

For the quantification of total zinc in the feed additive:

  • Inductively coupled plasma atomic emission spectrometry, ICP-AES (BS EN 15510:2017120 or BS EN 15621:2017121); or
  • Atomic absorption spectrometry, AAS (BS EN ISO 6869:2001122)

For the quantification of total zinc in premixtures:

  • Inductively coupled plasma atomic emission spectrometry, ICP-AES (BS EN 15510:2017 or BS EN 15621:2017); or

  • Atomic absorption spectrometry, AAS (BS EN ISO 6869:2001); or

  • Inductively coupled plasma mass spectrometry, ICP-MS (BS EN 17053:2018123)

For the quantification of total zinc in feed materials and compound feed:

  • Inductively coupled plasma atomic emission spectrometry, ICP-AES (BS EN 15510:2017 or BS EN 15621:2017); or

  • Atomic absorption spectrometry, AAS (in accordance with Commission Regulation (EC) 152/2009 (Annex IV, C) or BS EN ISO 6869:2001); or

  • Inductively coupled plasma mass spectrometry, ICP-MS (BS EN 17053:2018)

Species or category of animal

All animal species

Maximum age

Not applicable

Content of zinc (Zn) (mg/kg of complete feed with a moisture content of 12%)

Minimum content

No minimum

Maximum content

  • Dogs and cats: 200 mg/kg (total)

  • Salmonids and milk replacers for calves: 180 mg/kg (total)

  • Piglets, sows, rabbits and all fish other than salmonids: 150 mg/kg (total)

  • Other animal species: 120 mg/kg (total)

Other provisions

1.

The additive must be incorporated into feed in the form of a premixture.

2.

Zinc chelate of hydroxy analogue of methionine may be placed on the market and used as an additive consisting of a preparation.

Schedule 20Authorisation of a preparation of fumonisin esterase (EC 3.1.1.87) produced by fermentation with Komagataella phaffii (DSM 32159) (identification number 1m03i) as a feed additive for all animal species, for use only in maize-based silages

Regulation 3

The preparation of fumonisin esterase (EC 3.1.1.87) produced by fermentation with Komagataella phaffii (DSM 32159), belonging to the additive category ‘technological’ and to the functional group ‘substances for reduction of the contamination of food by mycotoxins: fumonisins’, is authorised as an additive in animal nutrition, in accordance with the specifications in the following table.

Additive

Fumonisin esterase (EC 3.1.1.87)

Identification number

1m03i

Authorisation holder124

None

Additive category

Technological

Functional group

Substances for reduction of the contamination of feed by mycotoxins: fumonisins

Additive composition

  • Preparation of fumonisin esterase (EC 3.1.1.87) produced by fermentation with Komagataella phaffii (DSM 32159) having a minimum enzyme activity of 3,000 U/g 125

Characterisation of the active substance(s)

Fumonisin esterase (EC 3.1.1.87) produced by Komagataella phaffii (DSM 32159)

  • EC (IUBMB) no: 3.1.1.87

Analytical method126

For the determination of fumonisin esterase activity:

  • High performance liquid chromatography coupled with a tandem mass spectrometry (HPLC-MS/MS) method based on the quantification of the tricarballylic acid released from the action of the enzyme on fumonisin B1 at pH 8.0 and 30°C

Species or category of animal

All animal species

Maximum age

Not applicable

Units of activity/kg of fresh material

Minimum content

40 U/kg

Maximum content

No maximum

Other provisions

1.

The storage conditions and stability to heat treatment must be stated in the directions for use of the feed additive and premixture.

2.

The use of the additive is only authorised in maize-based silages.

Schedule 21Revocation of assimilated direct legislation

Regulation 17

Part 1Revocation of assimilated direct legislation in accordance with regulation 17(1)

1.

Commission Regulation (EU) No 333/2010 concerning the authorisation of a new use of Bacillus subtilis C-3102 (DSM 15544) as a feed additive for weaned piglets (holder of authorisation Asahi Calpis Wellness Co. Ltd, represented in the European Union by Pen & Tec Consulting S.L.U.)127.

2.

Commission Regulation (EU) No 335/2010 concerning the authorisation of zinc chelate of hydroxy analogue of methionine as a feed additive for all animal species128.

3.

Commission Regulation (EU) No 349/2010 concerning the authorisation of copper chelate of hydroxy analogue of methionine as a feed additive for all animal species129.

4.

Commission Regulation (EU) No 350/2010 concerning the authorisation of manganese chelate of hydroxy analogue of methionine as a feed additive for all animal species130.

5.

Commission Regulation (EU) No 170/2011 concerning the authorisation of Saccharomyces cerevisiae MUCL 39885 as a feed additive for piglets (weaned) and amending Regulation (EC) No 1200/2005 (holder of authorisation Prosol SpA)131.

6.

Commission Regulation (EU) No 184/2011 concerning the authorisation of Bacillus subtilis C-3102 (DSM 15544) as a feed additive for chickens reared for laying, turkeys, minor avian species and other ornamental and game birds (holder of authorisation Asahi Calpis Wellness Co. Ltd, represented in the European Union by Pen & Tec Consulting S.L.U.)132.

7.

Commission Implementing Regulation (EU) No98/2012 concerning the authorisation of 6-phytase (EC 3.1.3.26) produced by Pichia pastoris (DSM 23036) as a feed additive for chickens and turkeys for fattening, chickens reared for laying, turkeys reared for breeding, laying hens, other avian species for fattening and laying, weaned piglets, pigs for fattening and sows (holder of authorisation Huvepharma AD)133.

8.

Commission Implementing Regulation (EU) 2019/893 concerning the renewal of the authorisation of Bacillus subtilis DSM 15544 as a feed additive for chickens for fattening and repealing Regulation (EC) No 1444/2006 (holder of authorisation Asahi Calpis Wellness Co. Ltd, represented in the European Union by Pen & Tec Consulting S.L.U.)134.

9.

Commission Implementing Regulation (EU) 2020/146 amending Regulation (EU) No333/2010, Implementing Regulation (EU) 2017/2312, Implementing Regulation (EU) 2018/1081, Implementing Regulation (EU) 2016/897, Implementing Regulation (EU) 2019/893 and Regulation (EU) No184/2011 concerning the authorisation of the preparation of Bacillus subtilis C-3102 (DSM 15544) as a feed additive135.

Part 2Revocation of assimilated direct legislation in accordance with regulation 17(2)

10.

Commission Regulation (EC) No 109/2007 concerning the authorisation of monensin sodium (Coxidin) as a feed additive136.

11.

Commission Implementing Regulation (EU) No140/2012 concerning the authorisation of monensin sodium as a feed additive for chickens reared for laying (holder of authorisation Huvepharma NV Belgium)137.
Explanatory Note
(This note is not part of the Regulations)

These Regulations make provision, in relation to England, in relation to animal feed additive authorisations, and in relation to a use of feed for a particular nutritional purpose.

Regulation 3 and Schedules 1 - 20 contain the following authorisations—

  • Schedule 1 contains a new authorisation for a preparation of chromium chelate of DL-methionine (identification number GB4d0001).

  • Schedule 2 contains a renewal of an authorisation of a preparation of Saccharomyces cerevisiae (MUCL 39885) (identification number 4b1710, and new authorisation extending authorised uses to cover additional species/categories of animal.

  • Schedule 3 contains a new authorisation for a preparation of Pediococcus acidilactici (CNCM I-4622) (identification number 4d1712).

  • Schedule 4 and 5 contain a renewal (with modification) of an authorisation of preparations of monensin sodium produced by fermentation with Streptomyces cinnamonensis 28682 (NBIMCC 3419) (carriers: perlite and (respectively) calcium carbonate or wheat bran) (identification number 51701), and new authorisation extending authorised uses to cover an additional category of animal. The modifications on renewal are:

    • a correction to the description of an animals species/category (turkey) covered;

    • the removal of the requirement for a 1-day (before slaughter) withdrawal period.

  • Schedule 6 contains a renewal (with modification) of an authorisation of a preparation of 6-phytase (EC 3.1.3.26) produced by fermentation with Komagataella phaffii (DSM 23036) (identification number 4a16), and new authorisation extending authorised uses to cover additional species/categories of animals. See regulation 13 for transitional provision. The modifications on renewal are:

    • the name of the bacterial strain is updated to Komagataella phaffii (formerly Komagataella pastoris);

    • a requirement as to use listed under “other provisions” (relating to phosphorus content in feed) is removed.

  • Schedule 7 contains a renewal of authorisations (with modification) of a preparation of Bacillus velezensis (DSM 15544) (identification number 4b1820), and new authorisation extending and consolidating authorised uses to cover additional species of animal. See regulation 10 for transitional provision. The modifications on renewal are:

    • the name of the authorisation holder is updated;

    • the name of the bacterial strain is updated to Bacillus velezensis (formerly Bacillus subtilis);

    • the minimum content requirement for chickens reared for laying is reduced (from 5 × 108 to 3 × 108 CFU/kg) to align with the minimum content requirement for other avian species/categories.

  • Schedule 8 contains a new authorisation for a preparation of L-histidine monohydrochloride monohydrate produced by fermentation with Escherichia coli K-12 (KCCM 80212) (identification number 3c352i).

  • Schedule 9 contains a new authorisation for a preparation of L-tryptophan produced by fermentation with Escherichia coli (KCCM 80210) (identification number 3c440i).

  • Schedule 10 contains a new authorisation for a preparation of L-lysine sulphate produced by fermentation with by fermentation with Corynebacterium glutamicum (KCCM 80227) (identification number 3c324i).

  • Schedule 11 contains a new authorisation of the substance butylated hydroxyanisole (BHA) (identification number 1b320) as a feed additive for cats. BHA as a feed additive for cats is separately an ‘existing product’ for the purpose of Article 10 of EUR 2003/1831 – see regulation 12 for removal of the existing product status.

  • Schedule 12 contains a new authorisation of a preparation of L-lysine base (liquid) produced by fermentation with Corynebacterium glutamicum (KCCM 80183) (identification number 3c320).

  • Schedule 13 contains a new authorisation of the substance L-lysine monohydrochloride (technically pure) produced by fermentation with Corynebacterium glutamicum (KCCM 80183) (identification number 3c322ii).

  • Schedule 14 contains a new authorisation of the substance disodium 5’-guanylate (GMP) produced by fermentation with Corynebacterium stationis (KCCM 10530) and Escherichia coli K-12 (KFCC 11067) (identification number 2b627i).

  • Schedule 15 contains a new authorisation of a preparation of muramidase produced by fermentation with Trichoderma reesei (DSM 32338) (identification number 4d16).

  • Schedule 16 contains a new authorisation of the substance phytomenadione (vitamin K1) (identification number 3a712).

  • Schedule 17 contains a renewal of authorisation (with modification) of a preparation of copper chelate of hydroxy analogue of methionine (identification number 3b410i). See regulation 14 for transitional provision. The modifications on renewal are:

    • the identification number is changed from 3b4.10 to 3b410i;

    • there are changes to the composition of the authorised preparation;

    • a maximum level of for nickel (20 ppm) is added;

    • the analytical methods are updated.

  • Schedule 18 contains a renewal of authorisation (with modification) of a preparation of manganese chelate of hydroxy analogue of methionine (identification number 3b510). See regulation 15 for transitional provision. The modifications on renewal are:

    • the identification number is changed from 3b5.10 to 3b510;

    • there are changes to the specification of the authorised preparation;

    • a maximum level for nickel (170 ppm) is added;

    • the analytical methods are updated.

  • Schedule 19 contains a renewal of authorisation (with modification) of a preparation of zinc chelate of hydroxy analogue of methionine (identification number 3b610. See regulation 16 for transitional provision. The modifications on renewal are:

    • the identification number is changed from 3b6.10 to 3b610;

    • there are changes to the specification of the authorised preparation;

    • a maximum level for nickel (1.7 ppm) is added;

    • the analytical methods have been updated.

  • Schedule 20 contains a new authorisation of a preparation of fumonisin esterase (EC 3.1.1.87) as a feed additive for all animal species, for use only in maize-based silages.

Authorisations granted by these Regulations are valid for a period of ten years in accordance with Article 9(7) of Regulation (EC) No 1831/2003 (EUR 2003/1831). This is subject to Article 14(4) of that Regulation, which provides for an extension of the authorisation period in certain circumstances where an application for renewal has been submitted.

Part 3 (regulation 4) is made in exercise of powers in the Agriculture Act 1970 (1970 c. 40). Regulation 4 amends Commission Regulation (EU) 2020/354 establishing a list of intended uses of feed intended for particular nutritional purposes, etc. An amendment is made to an essential nutritional characteristic for the lawful marketing of feed intended for use for the reduction of the risk of milk fever and subclinical hypocalcemia.

Regulation 5 amends certain instruments containing authorisations for the feed additive Bacillus velezensis (DSM 15544). The authorisations are modified to update the name of the authorisation holder, and to update the name of the bacterial strain Bacillus velezensis (formerly Bacillus subtilis C-3102).

Regulation 5(1) amends Commission Implementing Regulation (EU) 2016/897 concerning the authorisation of a preparation of Bacillus subtilis (C-3102) (DSM 1544) as a feed additive for laying hens and ornamental fish, etc., to remove the authorisation for Bacillus velezensis (DSM 15544) in relation to laying hens. That authorisation is superseded by, and consolidated within, the authorisation contained in Schedule 7.

Regulation 6 amends Commission Implementing Regulation (EU) 2019/804 concerning the renewal of the authorisation of organic form of selenium produced by Saccharomyces cerevisiae CNCM I-3060 and of selenomethionine produced by Saccharomyces cerevisiae NCYC R397 as feed additives for all animal species, etc., which contains an authorisation for the feed additive selenised yeast produced by fermentation with Saccharomyces cerevisiae CNCM I-3060, inactivated, with the identification number 3b810. The authorisation is modified in relation to the permitted selenium content of the additive, and to introduce a requirement in relation to the dusting potential of the additive. See regulation 12 for transitional provision.

Regulation 7 amends a number a instruments to update the name of the authorisation holder.

Regulations 8 and 9 make minor consequential amendments.

Regulation 12 makes provision to remove the authorisation in relation to butylated hydroxyanisole as a feed additive for cats as an existing product under Article 10 of EUR 2003/1831. To remain on the market as feed additive for cats, the additive must comply with the conditions of the new authorisation contained in Schedule 11 to these Regulations. Regulation 12 makes transitional provision to allow existing products (that cannot comply with the new authorisation) produced and labelled within specified periods to continue to be markets and used until stocks are exhausted.

Part 5 (regulations 10 to 16) of these Regulations contains transitional provisions in relation to feed additive authorisations that are modified or renewed by the Regulations. The transitional provisions allow the continued production and labelling of specified feed additives and products containing them, for limited time periods, under the conditions of authorisation applicable immediately before these Regulations come into force. Products produced and labelled within the transitional periods may be marketed and used until stocks are exhausted.

Regulation 17 and Schedule 21 revoke, in relation to England, assimilated direct legislation that contain previous authorisations for feed additives now authorised by Schedules 2 to 7, 11, 18 and 19.

Hard copies of the documents in the Schedules are available for inspection at the Food Standards Agency, Food House, Kings Pool, 1-2 Peasholme Green, York YO1 7PR following a written request to that address or to FeedAdditives@food.gov.uk.

An impact assessment has not been produced for this instrument as no, or no significant, impact on the public, private or voluntary sector is foreseen.