18.—(1) A user who undertakes a contained use involving micro-organisms must ensure that the risks to human health and the environment arising from the contained use are reduced to the lowest level that is reasonably practicable.
(2) The measures to be taken in order to comply with the duty under paragraph (1) must include the general principles of good microbiological practice and of good occupational safety and hygiene set out in Schedule 7.
(3) A user who undertakes a contained use involving larger GMOs must ensure that the risks to human health arising from the contained use are reduced to the lowest level that is reasonably practicable.
(4) For contained use involving larger GMOs, the general principles set out in Schedule 7 must be applied to the extent that they are appropriate.