SCHEDULE 2CRITERIA FOR THE CLASSIFICATION OF ORGANISMS
PART ICriteria as applicable for classification of micro-organisms in Group I
Vectors/Insert2
a
well characterised and free from known harmful sequences;
b
limited in size as much as possible to the genetic sequences required to perform the intended function;
c
should not increase the stability of the construct in the environment (unless that is a requirement of intended function);
d
should be poorly mobilisable;
e
should not transfer any resistance markers to micro-organisms not known to acquire them naturally (if such acquisition could compromise use of drugs to control disease agents).