Search Legislation

Advanced Search

2002/106/EC: Commission DecisionShow full title

2002/106/EC: Commission Decision of 1 February 2002 approving a Diagnostic Manual establishing diagnostic procedures, sampling methods and criteria for evaluation of the laboratory tests for the confirmation of classical swine fever (Text with EEA relevance) (notified under document number C(2002) 381)

Help about what version

What Version

More Resources

Revised version PDFs

Help about UK-EU Regulation

Legislation originating from the EU

When the UK left the EU, legislation.gov.uk published EU legislation that had been published by the EU up to IP completion day (31 December 2020 11.00 p.m.). On legislation.gov.uk, these items of legislation are kept up-to-date with any amendments made by the UK since then.

Close

This item of legislation originated from the EU

Legislation.gov.uk publishes the UK version. EUR-Lex publishes the EU version. The EU Exit Web Archive holds a snapshot of EUR-Lex’s version from IP completion day (31 December 2020 11.00 p.m.).

Changes to legislation:

There are currently no known outstanding effects by UK legislation for 2002/106/EC: Commission Decision. Help about Changes to Legislation

Close

Changes to Legislation

Revised legislation carried on this site may not be fully up to date. At the current time any known changes or effects made by subsequent legislation have been applied to the text of the legislation you are viewing by the editorial team. Please see ‘Frequently Asked Questions’ for details regarding the timescales for which new effects are identified and recorded on this site.

  1. Introductory Text

  2. Article 1.(1) The Secretary of State, with the consent of each...

  3. Article 2.Annexes I and IV to Council Directive 80/217/EEC of 22...

  4. Article 3.This Decision shall apply from 1 November 2002.

  5. Article 4.This Decision is addressed to the Member States.

  6. Signature

    1. ANNEX

      CLASSICAL SWINE FEVER DIAGNOSTIC MANUAL

      1. CHAPTER I Introduction, objectives and definitions

        1. 1. In order to ensure uniform procedures to diagnose classical swine...

          1. (a) provides guidelines and minimum requirements on diagnostic procedures, sampling methods...

          2. (b) establishes minimum bio-safety requirements and quality standards to be observed...

          3. (c) establishes the laboratory tests to be used for the diagnosis...

        2. 2. This Manual is principally directed towards the authorities responsible for...

        3. 3. For the purpose of this Manual, in addition to the...

          1. (a) "suspected holding" means any pig holding which contains one or...

          2. (b) "singleton reactors" means any pig which yields a positive result...

          3. (c) "epidemiological sub-unit" or "sub-unit" means the building, place or land...

          4. (d) "in-contact pigs" means the pigs which lived in a holding...

      2. CHAPTER II Description of classical swine fever with emphasis on differential diagnosis

        1. A. Introduction

          1. 1. Classical swine fever is caused by an enveloped RNA virus...

          2. 2. Classical swine fever virus is relatively stable in moist excretions...

          3. 3. The main natural route of infection is oro-nasal by direct...

          4. 4. The incubation period in individual animals is about one week...

          5. 5. The clinical signs of classical swine fever are extremely variable...

          6. 6. Acute, chronic and prenatal forms of classical swine fever can...

        2. B. Acute form

          1. 1. Weaners and fattening pigs most often display the acute form...

          2. 2. Classical swine fever virus causes severe leukopenia and immunosuppression, which...

          3. 3. Pathological changes visible on post-mortem examination are most frequently observed...

          4. 4. In general the acute form of African swine fever leads...

          5. 5. Classical swine fever virus is shed in saliva, urine and...

        3. C. Chronic form

          1. 1. The chronic course of infection occurs when pigs are not...

          2. 2. Pathological changes are less typical, especially haemorrhages in organs and...

          3. 3. As clinical signs of chronic classical swine fever are rather...

        4. D. Prenatal form and late onset of disease

          1. 1. Classical swine fever virus is able to pass across the...

          2. 2. Detection of classical swine fever may be particularly difficult in...

      3. CHAPTER III Guidelines on main criteria to be considered for the recognition of a holding as a classical swine fever suspected holding

      4. CHAPTER IV Checking and sampling procedures

        1. A. Guidelines and procedures for clinical examination and sampling on pigs...

          1. 1. The appropriate Minister shall ensure that appropriate clinical examinations, sampling...

          2. 2. When an official veterinarian visits a suspected holding to confirm...

          3. 3. When reference is made to this paragraph, the clinical examination...

          4. 4. If dead or moribund pigs are detected in a suspected...

          5. 5. If further clinical signs or lesions that may suggest classical...

          6. 6. If the suspicion of classical swine fever in the holding...

          7. 7. If, after the examination carried out in a suspected holding,...

        2. B. Sampling procedures in a holding when pigs are killed following...

          1. 1. In order that the manner of introduction of classical swine...

          2. 2. The minimum number of pigs to be sampled must allow...

          3. 3. However, in case of secondary outbreaks, the competent authority may...

        3. C. Sampling procedures when pigs are killed as a preventive measure...

          1. 1. In order that classical swine fever may be confirmed or...

          2. 2. Sampling must primarily concern:

        4. D. Checking and sampling procedures before authorisation is given to move...

          1. 1. Without prejudice to the provisions of Article 11(1)(f), second subparagraph...

          2. 2. In the case of pigs to be moved to another...

          3. 3. In case of pigs to be moved to a slaughterhouse,...

          4. 4. When the pigs referred to in subparagraph 3 are slaughtered...

          5. 5. However, if clinical signs or post-mortem lesions suggesting classical swine...

        5. E. Checking and sampling procedures in a holding in relation to...

          1. 1. When pigs are re-introduced into a holding in accordance with...

          2. 2. After re-introduction of pigs, the competent authority shall ensure that...

        6. F. Sampling procedures in holdings in the protection zone before lifting...

          1. 1. In order that the measures referred to in Article 10...

          2. 2. The minimum number of blood samples to be taken must...

        7. G. Sampling procedures in holdings in the surveillance zone before lifting...

          1. 1. In order that the restrictions referred to in Article 11...

          2. 2. Whenever blood sampling for serological tests is carried out in...

        8. H. Serological monitoring and sampling procedures in areas where classical swine...

          1. 1. In the case of serological monitoring in feral pigs in...

          2. 2. If data on population density and size are not available,...

          3. 3. Without prejudice to the provisions of Article 15(2)(c) of Directive...

          4. 4. Collection of samples for virological tests from feral pigs shot...

          5. 5. All samples to be sent to the laboratory must be...

      5. CHAPTER V General procedures and criteria for collection and transport of samples

        1. A. General procedures and criteria

          1. 1. Before sampling is carried out in a suspected holding, a...

          2. 2. Each time that it is deemed that re-sampling of pigs...

          3. 3. Without prejudice to Chapter IV A. 5.b, samples for serological...

          4. 4. All samples must be sent to the laboratory accompanied by...

        2. B. Collection of samples for virological tests

          1. 1. For detection of classical swine fever virus, antigen or genome...

          2. 2. Anticoagulated blood or clotted blood samples must be collected from...

          3. 3. Virological tests are recommended in the case of sick animals....

        3. C. Transport of samples

          1. 1. It is recommended that all samples: are transported and stored...

          2. 2. The outside of the package must be labelled with the...

          3. 3. The laboratory receiving the samples must be informed in advance...

          4. 4. For air transport of samples to the Community Reference Laboratory...

      6. CHAPTER VI Principles and use of virological tests and evaluation of their results

        1. A. Detection of virus antigen

          1. 1. Fluorescent antibody test (FAT)

          2. 2. ELISA for antigen detection

        2. B. Virus isolation

          1. 1. Virus isolation is based on the incubation of sample material...

          2. 2. The preferred samples for isolation of classical swine fever virus...

          3. 3. Virus isolation is best suited for the investigation of samples...

          4. 4. It is recommended to perform virus isolation also in case...

          5. 5. All classical swine fever virus isolates from all primary outbreaks,...

        3. C. Detection of virus genome

          1. 1. The polymerase chain reaction (PCR) is applied to detect virus...

          2. 2. PCR can be used on small numbers of samples which...

          3. 3. Suitable sample material for diagnostic PCR are the organs described...

          4. 4. PCR can be performed within 48 hours. It requires appropriate...

        4. D. Evaluation of the results of virological tests

          1. 1. Virological tests are essential for the confirmation of classical swine...

          2. 2. A positive result for classical swine fever to a genome...

        5. E. Genetic typing of classical swine fever virus isolates

          1. 1. Genetic typing of classical swine fever virus isolates is achieved...

          2. 2. ...

      7. CHAPTER VII Principles and use of serological tests and evaluation of their results

        1. A. Basic principles and diagnostic value

          1. 1. In classical swine fever virus infected pigs, antibodies are usually...

          2. 2. The detection of antibodies against classical swine fever virus in...

        2. B. Recommended serological tests

          1. 1. The virus neutralisation test (VNT) and the ELISA are the...

          2. 2. The VNT is based on the determination of the virus...

          3. 3. The VNT is the most sensitive and reliable test to...

          4. 4. The pestiviruses strains to be used in the neutralisation tests...

          5. 5. Several ELISA techniques using specific monoclonal antibodies have been developed,...

          6. 6. Quality control on sensitivity and specificity of each batch of...

          7. 7. The sensitivity of the ELISA is regarded as lower than...

        3. C. Interpretation of serological results and differential diagnosis with infections due...

          1. 1. Without prejudice to the provisions of Article 4(3)(a) or Article...

          2. 2. If the comparative tests show antibodies to ruminant pestiviruses and...

          3. 3. If the comparative tests show a virus neutralisation titre in...

          4. 4. Without prejudice to the provisions of Article 4(3) of Directive...

          5. 5. However, if the further checks and tests referred to in...

      8. CHAPTER VIII Discriminatory tests in case of emergency vaccination

        1. A. Basic principles

          1. 1. A discriminatory serological ELISA test (discriminatory test) is available to...

          2. 2. The discriminatory test is a liquid phase blocking enzyme-linked immunoassay....

        2. B. Guidelines for the use of the discriminatory test in the...

      9. CHAPTER IX Minimum safety requirements for classical swine fever laboratories

        1. 1. The minimum requirements laid down in Table 1 must be...

        2. 2. The additional requirements laid down in Table 1 must be...

        3. 3. The requirements laid down in Table 2 must be fulfilled...

        4. 4. In any case, all stocks of classical swine fever virus...

        5. 5. It is recommended that the bio-safe unit for classical swine...

Back to top

Options/Help

Print Options

Close

Legislation is available in different versions:

Latest Available (revised):The latest available updated version of the legislation incorporating changes made by subsequent legislation and applied by our editorial team. Changes we have not yet applied to the text, can be found in the ‘Changes to Legislation’ area.

Original (As adopted by EU): The original version of the legislation as it stood when it was first adopted in the EU. No changes have been applied to the text.

Close

Opening Options

Different options to open legislation in order to view more content on screen at once

Close

More Resources

Access essential accompanying documents and information for this legislation item from this tab. Dependent on the legislation item being viewed this may include:

  • the original print PDF of the as adopted version that was used for the EU Official Journal
  • lists of changes made by and/or affecting this legislation item
  • all formats of all associated documents
  • correction slips
  • links to related legislation and further information resources
Close

Timeline of Changes

This timeline shows the different versions taken from EUR-Lex before exit day and during the implementation period as well as any subsequent versions created after the implementation period as a result of changes made by UK legislation.

The dates for the EU versions are taken from the document dates on EUR-Lex and may not always coincide with when the changes came into force for the document.

For any versions created after the implementation period as a result of changes made by UK legislation the date will coincide with the earliest date on which the change (e.g an insertion, a repeal or a substitution) that was applied came into force. For further information see our guide to revised legislation on Understanding Legislation.

Close

More Resources

Use this menu to access essential accompanying documents and information for this legislation item. Dependent on the legislation item being viewed this may include:

  • the original print PDF of the as adopted version that was used for the print copy
  • correction slips

Click 'View More' or select 'More Resources' tab for additional information including:

  • lists of changes made by and/or affecting this legislation item
  • confers power and blanket amendment details
  • all formats of all associated documents
  • links to related legislation and further information resources

The data on this page is available in the alternative data formats listed: