3.2.2.7.Determination of No Observed Adverse Effect Levels (NOAEL)
The NOAEL is generally based on toxicological effects, but pharmacological effects might occasionally be more appropriate.
The lowest NOAEL shall be selected. All findings from previous sections together with all other relevant published data (including any relevant information on the effects of the active substance on human) and information, where appropriate, on chemicals having a closely related chemical structure shall be taken into consideration in identifying the lowest NOAEL, expressed as mg per kg body weight per day.