Where one or more Member States raise a substantial difficulty resulting from the implementation of the Trade and Cooperation Agreement, in particular with regard to fisheries, the Commission shall examine that request as a matter of priority and shall seize as appropriate the Partnership Council of that matter, in accordance with the provisions set out in the Trade and Cooperation Agreement. Where no satisfactory solution has been found, that matter shall be addressed within the earliest possible timeframe, in the context of the reviews provided for in the Trade and Cooperation Agreement. Where that difficulty persists, the necessary steps shall be taken with a view to negotiating and concluding an agreement making the necessary amendments to the Trade and Cooperation Agreement.