In case of an outbreak of HPAI, the competent authority shall ensure that the measures provided for in Article 3(2) and (3) and paragraphs 2 to 9 of this Article are applied.

All poultry and other captive birds on the holding shall be killed without delay under official supervision. The killing shall be carried out in such a way as to avoid the risk of spread of avian influenza, in particular during transport.

However, Member States may grant derogations for certain species of poultry or other captive birds not to be killed, on the basis of an assessment of the risk of further spread of avian influenza.

The competent authority may take appropriate measures to limit any possible spread of avian influenza to any wild birds on the holding.

All carcases and eggs on the holding shall be disposed of under official supervision.

Poultry already hatched from eggs collected from the holding during the period between the probable date of introduction of HPAI on the holding and the application of the measures provided for in Article 3(2), shall be placed under official supervision and investigations shall be carried out.

Meat of poultry slaughtered and eggs collected from the holding during the period between the probable date of introduction of HPAI on the holding and the application of the measures provided for in Article 3(2) shall, wherever possible, be traced and disposed of under official supervision.

All substances, manure and waste likely to be contaminated, such as feed, shall be destroyed or undergo a treatment ensuring the destruction of the avian influenza virus, in accordance with the instructions given by the official veterinarian.

Following the disposal of carcases, the buildings used for housing them, pastures or land, the equipment likely to be contaminated and the vehicles used for transporting the poultry or other captive birds, carcases, meat, feed, manure, slurry, bedding and any other material or substance likely to be contaminated shall undergo cleaning and disinfection with instructions given by the official veterinarian.

Other captive birds or mammals of domestic species shall not enter or leave the holding without the authorisation of the competent authority. That restriction shall not apply to mammals of domestic species which have access only to the living areas for humans.

In the case of a primary outbreak, the virus isolate shall be subjected to the laboratory investigations to identify the genetic subtype. That virus isolate shall be submitted to the Community reference laboratory for avian influenza referred to in Article 51(1) of Directive 2005/94/EC as soon as possible.