The Medicines (Prohibition of Non-medicinal Antimicrobial Substances) Order 1977 No. 2131

Article 2(1)

SCHEDULE 1 DESCRIPTIONS AND CLASSES OF ANTIMICROBIAL SUBSTANCES TO WHICH THE PROHIBITION IN ARTICLE 2(1) OF THIS ORDER APPLIES

PART I

• Amphomycin

• Bacitracin

• Candicidin

• Capreomycin

• Chloramphenicol

• Cycloserine

• Erythromycin

• Framycetin

• Furaltadone

• Furazolidone

• Fusidic Acid

• Griseofulvin

• Hachimycin

• Nalidixic Acid

• Nitrofurantoin

• Nitrofurazone

• Novobiocin

• Nystatin

• Oleandomycin

• Paromomycin

• Spectinomycin

• Spiramycin

• Tylosin

• Vancomycin

• Viomycin

• Virginiamycin

NOTE

In this Part of this Schedule—

(a)

a reference to any substance, other than furaltadone, shall be construed as a reference to the substance for which such name is shown in the current edition of the list of names prepared and published under section 100 of the Act, and

(b)

“furaltadone” means (±)-5-morpholino-methyl-3-(5-nitrofurylidene-amino)-2-oxo-oxazolidine.

PART II

Column 1	Column 2
Class of substance	Meaning
1. Amphotericins	1. Antimicrobial substances or mixtures of such substances produced by Streptomyces nodosus.
2. Cephalosporins	2. Antimicrobial substances containing in their chemical structure a fused dihydrothiazine β-lactam nucleus.
3. Gentamicins	3. Any antimicrobial basic substance or mixture of such substances produced by the strain Micromonospora purpurea which on 1st September 1967 was numbered NRRL 2953 in the culture collection of the Northern Utilisation Research and Development Branch of the United States Department of Agriculture.
4. Kanamycins	4. Any antimicrobial substance or mixture of such substances produced by Streptomyces Kanamyceticus.
5. Lincomycins	5. Antimicrobial substances produced by Streptomyces lincolnensis (var. lincolnensis). These substances are the basic amides of hygric acid or of a substituted hygric acid with 6-amino-6, 8-dideoxy-1-thiogalacto-octopyranose or with substituted 6-amino-6, 8-dideoxy-1-thiogalacto-octopyranose.
6. Neomycins	6. Antimicrobial substances or mixtures of such substances produced by Streptomyces fradiae which are complex organic bases and which yield on hydrolysis with mineral acids the base neamine.
7. Penicillins	7. Any antimicrobial acid which contains in its structure a fused thiazolidine β-lactam nucleus.
8. Polymixins	8. Any antimicrobial substance produced by any strain of Bacillus polymyxa.
9. Rifamycins	9. A group of related antimicrobial macrolactams produced by the growth of Streptomyces mediterranei and containing the chemical structure of 11-acetoxy-7,9, 15-trihydroxy-13-methoxy-2,6,8,10,12-pentamethylpentadeca-2,4, 14-trienoic acid amide attached by the nitrogen atom and by the oxygen atom in the 15-position respectively to the 7- and 2-positions of a 5,6, 9-trioxygenated 2, 4-dimethyl-1-oxonaptho (2, 1-b) furan.
10. Ristocetins	10. Antimicrobial substances produced by a strain of a Nocardia species referred to as Nocardia lurida.
11. Streptomycins	11. Any antimicrobial complex organic base or mixture of such bases produced by Streptomyces griseus which:— (a) yields on hydrolysis with mineral acids the base streptidine (meso-1 3-diguanidocyclohexane-2,4,5,6-tetraol); and (b) yields on hydrolysis by a 4 per cent solution of sodium hydroxide the substance maltol (3-hydroxy-2-methyl-8-pyrone).
12. Sulphanilamide	12. Sulphanilamide being p-aminobenzenesulphonamide, having any of the hydrogen atoms of either or both nitrogen atoms substituted by an equal number of univalent atoms or radicals.
13. Tetracyclines	13. Antimicrobial bases which contain the chemical structure naphthacene-2-carboxamide, hydrogenated to any extent and having each of the positions 1,3,10,11,12 and 12a substituted by a hydroxyl or an oxo group.