[F1 ANNEX U.K.

Textual Amendments

F1 Substituted by Commission Implementing Decision of 8 August 2012 amending Decision 2002/253/EC laying down case definitions for reporting communicable diseases to the Community network under Decision No 2119/98/EC of the European Parliament and of the Council (notified under document C(2012) 5538) (Text with EEA relevance) (2012/506/EU).

2. CASE DEFINITIONS OF COMMUNICABLE DISEASES U.K.

2.47. TUBERCULOSIS ( Mycobacterium tuberculosis complex) U.K.

Clinical Criteria U.K.

Any person with the following two:

• Signs, symptoms and/or radiological findings consistent with active tuberculosis in any site

AND

• A clinician’s decision to treat the person with a full course of anti-tuberculosis therapy

OR

A case discovered post-mortem with pathological findings consistent with active tuberculosis that would have indicated anti-tuberculosis antibiotic treatment had the patient been diagnosed before dying

Laboratory Criteria U.K.

• Laboratory criteria for case confirmation

  At least one of the following two:

  • Isolation of Mycobacterium tuberculosis complex (excluding Mycobacterium bovis -BCG) from a clinical specimen

  • Detection of Mycobacterium tuberculosis complex nucleic acid in a clinical specimen AND positive microscopy for acid-fast bacilli or equivalent fluorescent staining bacilli on light microscopy

• Laboratory criteria for a probable case

  At least one of the following three:

  • Microscopy for acid-fast bacilli or equivalent fluorescent staining bacilli on light microscopy

  • Detection of Mycobacterium tuberculosis complex nucleic acid in a clinical specimen

  • Histological appearance of granulomata

Epidemiological Criteria NA U.K.

Case Classification U.K.

A. Possible case U.K.

Any person meeting the clinical criteria

B. Probable case U.K.

Any person meeting the clinical criteria and the laboratory criteria for a probable case

C. Confirmed case U.K.

Any person meeting the clinical and the laboratory criteria for case confirmation]